منابع مشابه
Assessment of T helper 17-associated cytokines in third trimester of pregnancy
Background: Preeclampsia is a common pregnancy-specific disorder associated with significant maternal and fetal morbidity and mortality worldwide. It has been proposed that the imbalance between two CD4+ T cell subtypes, regulatory T cells (Treg) and T-helper 17 cells (Th17), is involved in the pathophysiology of preeclampsia. Objectives: To determine the serum levels of IL-17, IL-21, IL-23 and...
متن کاملCharacterization of effector T cells in dry eye disease.
PURPOSE Dry eye disease (DED) is associated with ocular surface inflammation that is thought to be mediated primarily by CD4 T cells. The purpose of this study was to investigate whether this T cell-mediated immune response is generated in the lymphoid compartment and to characterize the functional phenotype of the T cells activated in DED. METHODS DED was induced in female C57BL/6 mice by ex...
متن کاملDry Eye Disease
Dry eye disease (DED) is a clinically significant multifactorial disorder of the ocular surface and tear film as it results in ocular discomfort and visual impairment and predisposes the cornea to infections. It is important for the quality of life and tends to be a chronic disease. It is also common, as the prevalence is estimated between 5 % to 30 % and this increases with age. Therefore, it ...
متن کاملBiomarkers In Dry Eye Disease
Dry eye disease is a multifactorial chronic disorder of the ocular surface that affects up to 100 million people worldwide. During the pathogenesis of dry eye, impaired function of the lacrimal and meibomian glands results in hyposecretion of aqueous tear fluid, coupled with increased evaporation and instability of the tear film, which becomes increasingly hyperosmolar in character at more seve...
متن کاملT helper 1 and T helper 2 cytokines in atopic children with steroid-sensitive nephrotic syndrome.
INTRODUCTION A higher incidence of allergic disorders has been documented in children with steroid-sensitive nephrotic syndrome (SSNS); however, the role of cytokines associated with T helper 1 and T helper 2 cells is not fully elucidated. This study aimed to evaluate the role of T helper 1 and T helper 2 cytokines in both remission and activity phases among atopic versus nonatopic children wit...
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ژورنال
عنوان ژورنال: Experimental Eye Research
سال: 2013
ISSN: 0014-4835
DOI: 10.1016/j.exer.2013.08.013